GARY CARLSON ILLUSTRATION
Immunomodulation of Tcells resulting in the release of cytokines
Cell apoptosis is triggered by the binding of specific receptors on cancer cells
Mechanisms of dysregulation of the pathways
Perforin oligomerizes within the plasma membrane of the target tumor cell creating entry portals for granzymes
Cell death is initiated by a cascade of multiple innate molecules
An arterial stent has enhanced effectiveness when coated with cell non-proliferation drugs
Cell death is initiated by blocking proteasome function
In cancer cells the transcription of RNA from DNA is physically inhibited
Elevated levels of TNF causes pathological inflammation in multiple locations
APC binds to Tcell releasing cytotoxic chemicals that damage adjacent tissues
By binding to the estrogen receptors of cells the growth of breast cancer is inhibited
A monoclonal antibody linked with a cytotoxic agent is internalized in a malignant cell